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Раздел 12. РАЗНОЕ
THE GENETIC HEALTH EFFECT OF RADIATION AND THE RIGHT TO HEALTH OF SECOND GENERATION OF RADIATION VICTIMS - FROM HIROSHIM&NAGASAKI AND CHERNOBYL TO FUKUSHIMA Katsumi Furitsu M.D.Ph.D
National Institute of Biochemical Innovation, Health and Nutrition, Osaka, Japan
Scientists are trying to prove or understand the genetic health effect of radiation on human being from the study of these three fields: 1. Estimation from the results of animal experiments, especially the data of mammals such as mice, 2. Epidemiological study on children of survivors who were exposed to radiation, 3. Studies of molecular genetics (DNA mutations of germ-line cells, different features of RNA expression, etc.). We already have clear scientific evidences and consensus on induction of genetic effect of radiation from the various data of animal experiments. However, as for the epidemiological study and studies of molecular genetics, we have not yet reached a clear consensus in the case of human being.
The results of experiments on mice suggest: 1. The genetic health effect induced by radiation exposure is not a "specific disease" to radiation. It includes congenital disorders, cancers, non-cancer diseases and so on, which could also occur spontaneously and could be induced by other environmental factors. 2. The risk of the genetic health problems of radiation increases in proportion to the exposure dose of parents.
To protect the right to health of the second and further generations of radiation victims, it is urgently necessary to provide the social and medical support to them based on the "precautionary principle". In this regard, the situation of the second generation of survivors of victims in Hiroshima&Nagasaki and Chernobyl will be comparatively discussed in this report, and the future problem in Fukushima will be considered.
COMPLEX PROBLEM ON THYROID CANCER AMONG YOUNG PEOPLE AFTER THE CATASTROPHE AT THE FUKUSHIMA-1 NPP
Yoshida Y
Chernobyl Health Survey and Healthcare Support for the Victims - Japan Women's Network, Chiba, Japan
Seven and half years have passed since the catastrophe at the Fukusima-1 NPP in 2011. Thyroid Ultrasound Screening is carried out to people who were 18 years old or younger at the time of the nuclear accident in Fukushima prefecture, Subjects are almost 380 thousand. Thyroid Screening continues every two years until the age of 20, and at 5 year milestones thereafter. Currently the result of the 3rd screening has been published. By the beginning of June 2018, 199 young people with thyroid cancer or suspicious malignancy cases are found. The Oversight
Committee for Fukushima Health Management Survey insists their evaluation that «an increase in the detection of thyroid cancer is unlikely to be effects of radiation». Additionally, there has been a claim that Fukushima ultrasound examination is finding cancer that does not require surgery. But the surgeon of Fukushima medical university claims that there had needs to surgery.
On the other hand, a private Fund was established in 2016 to support children with thyroid cancer, including those who were resident in surround areas of Fukushima prefecture. Author works as a director of the Fund.
As the information gotten by the Fund, although it has been limited, published numbers of patient with thyroid cancer is underestimated and the prevalence of recurrence or metastasis of the cancer is found of about 10% of the patients after first surgery in Fukushima.
The complex problem on thyroid cancer among young people after the catastrophe at the Fukushima-1 NPP has been emerged and continued.
ВОЗРАСТНЫЕ ОСОБЕННОСТИ ИСХОДОВ ЛИХОРАДКИ НЕЯСНОГО ГЕНЕЗА
Антонова М. В., Гашиятуллина Э.Э., Когут Ю.П., Малинина Е.И., Черных К.А.
ФГБОУ ВО Тюменский ГМУ Минздрава России, Тюмень
Введение. Интерес к проблеме «лихорадки неясного генеза» связан прежде всего с прогнозированием исхода, который зачастую представляет огромную сложность и трудный дифференциально-диагностический поиск. Термин «лихорадка неясного генеза» введено в клиническую практику в 1961 году Petersdorf R.G. и Beeson P.B. но несмотря на этот факт, существует неоднозначность его трактовки среди педиатров, инфекционистов и терапевтов.
Цель исследования — проанализировать клинические исходы лихорадки неясного генеза в детской и взрослой популяциях г. Тюмень.
Материалы и методы. Критериями включения пациентов в исследование явилось наличие предварительного диагноза «Лихорадка неясного генеза» в медицинской документации при поступлении в период с января 2016 по декабрь 2017 года. Все пациенты (97 человек) разделены на две группы: первая группа (дети) — возраст от 7 месяцев до 17 лет (средний возраст 7,6±4,5), вторая группа (взрослые) — от 18 до 84 лет (средний возраст 40,28±12,6).
Результаты исследования. Длительность лихорадочного синдрома к моменту поступления в детской популяции составила 102,5±42,05 дней, в то время как у взрослых — 10,8±6,3 дней. Наряду с лихорадкой пациенты отмечали: общую слабость (80%-89%), головную боль (28%-58%), боли в животе (11%-13%), рвоту (13%-14%), наличие сыпи (8%-18%). Катаральный синдром в 2 раза чаще встречался у детей (р=0,3992). В изменениях клинического анализа кро-
РОССИЙСКИЙ ВЕСТНИК ПЕРИНАТОЛОГИИ И ПЕДИАТРИИ, 2018; 63:(4) ROSSIYSKIY VESTNIK PERINATOLOGY IPEDIATRII, 2018; 63:(4)
DOI: 10.21508/1027-4065-congress-2018
