Научная статья на тему 'PRIMARY RETROGRADE TIBIAL-PEDAL ACCESS IN PATIENTS WITH CRITICAL LIMB ISCHEMIA'

PRIMARY RETROGRADE TIBIAL-PEDAL ACCESS IN PATIENTS WITH CRITICAL LIMB ISCHEMIA Текст научной статьи по специальности «Медицинские науки и общественное здравоохранение»

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Ключевые слова
primary retrograde tibial-pedal access / primary retrograde distal access / critical lower limb ischemia / CLI / peripheral artery disease / PAD. / первичный ретроградный тибио-педальный доступ / первичный ретроградный дистальный доступ / критическая ишемия нижних конечностей / КИНК / заболевания периферических артерий / ЗПА.

Аннотация научной статьи по медицинским наукам и общественному здравоохранению, автор научной работы — Таджибаев Талгат Кыдыралиевич, Баубеков Альжан Алькешевич, Омаров Нурлыбек Оразкелиевич, Нуссипакынов Арман Кыдыркулович, Нурмаганбет Самал Тиморовна

The most common complications after percutaneous vascular interventions are complications at the site of access. The use of retrograde tibial-pedal access could reduce the risks of significant complications at the puncture site compared to traditional femoral access. Purpose: In this study, we aimed to determine the efficacy and safety of primary tibial-pedal access for revascularization of chronic total occlusion of the femoral-popliteal and infrapopliteal segments in patients with critical lower limb ischemia. Materials and Methods: We conducted a retrospective analysis of 18 patients from January 2022 to August 2024. Patients were selected according to the following criteria: patients with categories 3, 4, 5 according to the Rutherford classification and stages 3,4 according to the Fontaine classification; femoropopliteal (FP) lesion with or without involvement of the infrapopliteal (IP) segment; the presence of blood flow in one or more distal or pedal segments of the main arteries of the leg and foot; informed consent of patients for the intervention. Results: The overall procedural success rate of the intervention was 100%. The average age of patients was 74±5 years. The majority of the subjects were women (66.7%). Comorbidities such as diabetes mellitus (66.7%), arterial hypertension (55.5%), coronary artery disease (38.9%), and hyperlipidemia (77.8%) were diagnosed. The artery of choice in the majority of cases was the anterior tibial artery 13 (72.2%) Balloon angioplasty combined with stent placement was performed in 14 cases (77.8%). Minor bleeding at the puncture site occurred in 1 case (5.5%). There were no signs of major bleeding, hematomas, MALE, MACE, or death in any case. All patients experienced relief of pain of ischemic origin. Conclusion: Retrograde tibial-pedal access is technically easier with a tendency to fewer complications. This technique can be used as a primary procedure or as an alternative to antegrade femoral access in complex patients with a high risk of hematoma formation.

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PRIMARY RETROGRADE TIBIAL-PEDAL ACCESS IN PATIENTS WITH CRITICAL LIMB ISCHEMIA

Наиболее частыми осложнениями после чрескожных сосудистых вмешательств являются осложнения в месте доступа. Использование ретроградного дистального доступа позволяет снизить риски значимых осложнений в месте пункции по сравнению с традиционным бедренным доступом. Целью данного исследования было определение эффективности и безопасности первичного ретроградного дистального доступа для реваскуляризации хронических окклюзий бедренно-подколенного и берцового сегментов у пациентов с критической ишемией нижних конечностей. Материалы и Методы. Проведен ретроспективный анализ 18 пациентов в Центре спасения конечностей клиники Private Clinic Almaty с января 2022 года по август 2024 года. Пациенты отбирались по следующим критериям: пациенты с 3,4,5 категорями по классификации Рудерфорда и 3,4 стадиями по классификации Фонтейна; поражение бедренно-подколенного с вовлечением или без вовлечения берцового сегмента; наличие кровотока в одном или нескольких мегстральных артерий голени и стопы; информированное согласие пациентов на вмешательство. Результаты. Успешность процедуры составил 100%. Средний возраст пациентов составил 74±5 лет. Большинство пациентов были женщинами (66,7%). Диагностированы такие сопутствующие заболевания, как сахарный диабет (66,7%), артериальная гипертензия (55,5%), ишемическая болезнь сердца (38,9%) и гиперлипидемия (77,8%). Артерией выбора в большинстве случаев была передняя большеберцовая артерия 13 (72,2%). Из всех вмешательств малое кровотечение в месте пункции наблюдалось в 1 случае (5,5%). Ни в одном случае не было признаков значимого кровотечения, гематомы, нежелательных сердечно-сосудистых событий или смерти. У всех пациентов наблюдалось купирование болевого синдрома ишемического характера. Выводы. Ретроградный первичный дистальный доступ технически проще и имеет тенденцию к меньшему количеству осложнений. Этот метод может быть применен в качестве основного доступа или как альтернатива антеградному бедренному доступу у сложных пациентов с высоким риском образования гематомы

Текст научной работы на тему «PRIMARY RETROGRADE TIBIAL-PEDAL ACCESS IN PATIENTS WITH CRITICAL LIMB ISCHEMIA»

УДК: 616.13-089 DOI 10.24412/2790-1289-2024-3-10-19

МРНТИ: 76.29.30

PRIMARY RETROGRADE TIBIAL-PEDAL ACCESS IN PATIENTS WITH CRITICAL LIMB ISCHEMIA

*T.K Tajibayev, A.A Baubekov, N.O Omarov, A.K. Nussipakynov, S.T. Nurmaganbet

«Private Clinic Almaty», Kazakhstan, Almaty * Corresponding author

Abstract

The most common complications after percutaneous vascular interventions are complications at the site of access. The use of retrograde tibial-pedal access could reduce the risks of significant complications at the puncture site compared to traditional femoral access.

Purpose: In this study, we aimed to determine the efficacy and safety of primary tibial-pedal access for revascularization of chronic total occlusion of the femoral-popliteal and infrapopliteal segments in patients with critical lower limb ischemia.

Materials and Methods: We conducted a retrospective analysis of 18 patients from January 2022 to August 2024. Patients were selected according to the following criteria: patients with categories 3, 4, 5 according to the Rutherford classification and stages 3,4 according to the Fontaine classification; femoropopliteal (FP) lesion with or without involvement of the infrapopliteal (IP) segment; the presence of blood flow in one or more distal or pedal segments of the main arteries of the leg and foot; informed consent of patients for the intervention.

Results: The overall procedural success rate of the intervention was 100%. The average age of patients was 74±5 years. The majority of the subjects were women (66.7%). Comorbidities such as diabetes mellitus (66.7%), arterial hypertension (55.5%), coronary artery disease (38.9%), and hyperlipidemia (77.8%) were diagnosed. The artery of choice in the majority of cases was the anterior tibial artery 13 (72.2%) Balloon angioplasty combined with stent placement was performed in 14 cases (77.8%). Minor bleeding at the puncture site occurred in 1 case (5.5%). There were no signs of major bleeding, hematomas, MALE, MACE, or death in any case. All patients experienced relief of pain of ischemic origin.

Conclusion: Retrograde tibial-pedal access is technically easier with a tendency to fewer complications. This technique can be used as a primary procedure or as an alternative to antegrade femoral access in complex patients with a high risk of hematoma formation.

Keywords: primary retrograde tibial-pedal access, primary retrograde distal access, critical lower limb ischemia, CLI, peripheral artery disease, PAD.

Introduction

Critical limb ischemia (CLI) is the terminal stage of occlusive peripheral arterial disease and is characterized by chronic pain at rest and loss of tissue and limbs. The annual incidence of CLI is 100 cases per 100,000 population, and mortality reaches more than 20% in the first 6 months after diagnosis [1]. The most common causes of CLI are atherosclerosis and vascular complications of diabetes mellitus [2, 3]. There is a close connection between diabetes mellitus and CLI [4]. Every year, more

than 1 million lower limb amputation operations are performed in the world for diabetes mellitus, more than 600 thousand patients lose their eyesight, approximately 500 thousand patients develop kidney failure [4].

Currently, there are open, endovascular and hybrid methods of vein arterialization with various modifications and technologies. However, there are no large studies in the modern literature comparing the safety and efficacy of these methods in the short and long term [5]. Traditionally, endovascular methods of

revascularization of both the femoral-popliteal and tibial-pedal segments are performed through antegrade ipsilateral femoral or retrograde contralateral femoral access. However, the most common complications after percutaneous vascular interventions are complications at the site of access [6, 7].

Complications at the site of access include hematoma of varying severity, as well as stenosis or occlusion of the site of access. Post-access groin hematomas can be treated expectantly with transfusions and thrombin injections only, but if a pseudoaneurysm is present, re-intervention by open surgery or endovascular means is necessary. The reasons for this may be obesity, calcified artery, stenosis, thickness of the introducer, experience of the surgeon and others [6]. According to various data, complications at the puncture site can reach up to 5%, of which up to 1% require surgical intervention [8].

Hypothetically, the use of retrograde tibio-pedal access could reduce the risks of significant complications at the puncture site compared to traditional femoral access, due to the smaller diameter of the artery and the proximity of the artery to the skin. In addition, the proximal "cap" of chronic total occlusion is often denser and presents difficulties with antegrade intraluminal recanalization even in experienced endovascular surgeons. In this regard, retrograde distal access can be considered as an alternative and safer approach to endovascular revascularization in order to save the limb.

A retrograde approach to endovascular recanalization of femoral-popliteal lesions was first described more than 30 years ago [9]. Most often, the target artery for puncture with retrograde access is the artery of the back of the foot and the anterior tibial artery, but it is also possible to puncture the posterior tibial or peroneal artery. Notably, there are limited data regarding the success rate and safety of Tronic total occlusion (CTO) intervention via retrograde access, as published studies have included only a few patients with femoro-popliteal CTO [10].

Purpose.

In this study, we aimed to determine the efficacy and safety of primary tibial-pedal access

for revascularization of chronic total occlusion of the femoral-popliteal and infrapopliteal segments in patients with critical lower limb ischemia.

Materials and Methods

We conducted a retrospective analysis of 18 patients at the Limb Salvage Center of the Private Clinic Almaty clinic from January 2022 to August 2024. All patients underwent ultrasound duplex scanning and CT angiography of the lower extremity arteries for diagnostics and planning of procedure.

Patients were selected according to the following criteria: patients with categories 3, 4, 5 according to the Rutherford classification and stages 3, 4 according to the Fontaine classification; femoropopliteal (FP) lesion with or without involvement of the infrapopliteal (IP) segment; the presence of blood flow in one or more distal or pedal segments of the main arteries of the leg and foot; informed consent of patients for the intervention. Relative indications were the obesity, flush- occlusion of the superficial femoral artery, calcified common femoral artery, severe comorbid background, rigid scars after previously open surgery in the groin on the ipsilateral side. Patients with secondary (auxiliary) retrograde distal access were excluded from the study. The target artery for access were a. tibialis anterior, a. dorsalis pedis, a. tibialis posterior, a. peronea.

In all cases, access was performed under duplex ultrasound navigation, a linear sensor was installed transversely or longitudinally to the access artery, a hydrophilic radial introducer 5F, 6F with a 22G needle was used. Access was performed under local anesthesia with Novokain 0.5%. To relieve arterial spasm, Verampamil, Nitroglycerin, or Papaverine were used. A TR Band pressure bandage was installed at the puncture site for 3 hours under ultrasound duplex navigation in all patients. Further observation of patients was carried out for 30 days.

The study complies with the Declaration of Helsinki and was approved by the Institutional Review Board. The authors and co-authors of the article have no conflicts of interest.

Results

According to the analysis the average age of patients was 74±5 years. Risk factors closely

associated with the development of CLI include advanced age, diabetes mellitus (DM), smoking, and female gender. The majority of the subjects were women (66.7%) with comorbidities such as diabetes mellitus (66.7%), arterial hypertension (55.5%), coronary artery disease (38.9%), and

Table 1. Baseline characteristics of patients.

hyperlipidemia (77.8%). A significant number of patients had a high BMI of 32±5.8. The majority of patients (83.3%) underwent primary intervention, while the remaining three patients had previously undergone interventions in the lesion area (Table 1).

Features N (%)

Age (years) 74 ± 4,7

Male/Female 6 (33,3%)/12 (66,7%)

Hypertension 10 (55,5%)

DM 12 (66,7%)

CAD 7 (38,9%)

Smoking 4 (22,2%)

CKD3 and above 2 (11,1%)

Hyperlipidemia 14 (77,8%)

BMI (kg/m2) 32 ± 5,8

Prior intervention 3 (16,7%)

Hemoglobin (g/l) 112 ± 21

DM=Diabetes Mellitus; CAD=Coronary Artery Disease; CKD=Chronic kidney disease; BMI=Body Mass Index.

Source: Made by authors

The overall procedural success rate of the intervention was 100%. The artery of choice in the majority of cases was the anterior tibial artery 13 (72.2%), while the peroneal artery was not used in any case. With one patient, after dissection of the anterior tibial artery, the approach was changed to the posterior tibial artery. In more than half of the cases, the femoropopliteal and ipsilateral tibial segment

Table 2. Procedural characteristics.

were revascularized (55.5%). Balloon angioplasty combined with stent placement was performed in 14 cases (77.8%). Drug eluting balloons (DEB) or drug coated balloons (DCB) were used only in 5 patients (27.8%), where the main indications for their use were previous interventions in this lesion area. (Table 2).

Features N(%)

Success rate 18 (100%)

Primary access to the target artery

ATA/a.dorsalis pedis 13 (72,2%)

PTA 5 (27,8%)

PA 0 (0%)

Revascularized segment

Femoro-popliteal (FP) 8 (44,4%)

Tibial 0 (0%)

FP+Tibial 10 (55,5%)

Type of intervention

Balloon angioplasty (POBA) 13 (72,2%)

Balloon angioplasty (DEB, DCB) 5 (27,8%)

Stent placement 14 (77,8%)

Time of fluoroscopy (min) 128 ± 46

Contrast volume (ml) 52 ± 18

Heparin volume (units) 6112± 1388

ATA=anterior tibial artery; PTA=posterior tibial artery; PA=peroneal artery; POBA=plain old balloon angioplasty; DEB=drug eluting balloon; DCB=drug coated balloon.

Source: Made by authors

Of all the interventions, there was minor bleeding at the puncture site in 1 case (5.5%), which did not require hemotransfusion and was resolved by using an additional pressure bandage. In one case, after insertion of the sheath, arterial dissection was observed, in connection with which it was decided

Table 3. Complications and 30-day follow-up.

Features N(%)

Immediate complications

Bleeding 1(5,5%) (minor)

Hematoma 0(0%)

Access artery occlusion 0(0%)

Access artery dissection 1(5,5%)

MALE 0(0%)

MACE 0(0%)

Death 0(0%)

30-day follow-up

Worsening kidney function 2(11,1%)

MALE 0(0%)

Access artery occlusion 0(0%)

MACE 0(0%)

Death 0(0%)

AV-fistula 0(0%)

MALE=major adverse limb events; MACE=major adverse cardiovascular events; AV-fistula=arterio-venous fistula.

Source: Made by authors

to use access through the other ipsilateral tibial artery with subsequent exposure with a balloon at the site of the first puncture. There were no signs of major bleeding, hematomas, MALE, MACE, or death in any case. All patients experienced relief of pain of ischemic origin. (Table 3).

Case report

87-year-old woman with critical limb ischemia and gangrene of 2nd and 3rd fingers. In past medical history she had CAD, DM and obesity (BMI=42 kg/m2). Prolonged chronic total occlusion of superficial femoral artery, posterior

tibial artery and peroneal artery was revealed in CT-angiography. Using primary retrograde access to a single ATA, blood flow to all segments was restored. After the procedure 2,3,4 fingers were amputated with fast healing of wounds. (Figure 1, Figure 2).

Figure 1. Technical features of retrograde tibial-pedal access. (A) Fluoroscopy showing the wire through the distal anterior tibial artery. (B) Introducer inserted percutaneously into the anterior tibial artery. (C) View after the successful revascularization of femoro-popliteal and infrapopliteal segments. (D) TR band placement and Introducer removing.

Source: Made by authors

Figure 2. Follow-up of wound healing after the procedure. (A) Gangrene of 2nd and 3rd fingers. (B) Second day after the amputation of fingers. (C) View after plastic surgery of the wound with local tissues of the 4th finger. (D) 2 weeks after the surgery.

Source: Made by authors

Discussion

CLI patients are prone to higher risk of limb loss (amputation) and cardiovascular complications. The main aim of CLI management is to decrease the limb amputation [11]. Retrograde transpedal or tibial access has been used as an alternative approach since 2005, along with the specialized CTO crossing and reentry devices. With improved equipment combined with antegrade and/or retrograde techniques, the success rate of endovascular therapy in the femoropopliteal (FP) CTO has significantly improved from 75% in 2001 to 81%-94% in 2014 [12, 13]. In many instances, retrograde access with tibio-pedal access (TPA) can facilitate procedural success. Recently, to prevent femoral access-related complications, transradial approach (TRA) and/or TPA may also be an acceptable treatment strategy for FP CTO.

Interestingly, in our cases, at 30-day follow up, all patients reported having symptomatic improvement, while there were no cases of acute limb ischemia, death, or worsening kidney dysfunction.

Conclusion

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Retrograde tibial-pedal access is technically easier and tends to have fewer complications. This technique can be used as a first step or as an alternative to antegrade femoral access in complex patients with a high risk of hematoma formation. Since this is a new technology, further research and understanding of its ideal use cases is needed.

References

1. Norgren L., Hiatt W. R., Dormandy J. A. et al. Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II) // J Vasc Surg. - 2007. - Vol. 45. - P. 5-67.

2. Faglia E., Paola L. D., Clerici G., Clerissi J. Graziani et al. Peripheral angioplasty as the first-choice revascularization procedure in diabetic patients with critical limb ischemia: prospective study of 993 consecutive patients hospitalized and followed between 1999 and 2003 // J Vacs Endovasc Surg. - 2005. - Vol. 29(6). - P. 620-627.

3. Chantelau E., Lee K. M., Jungblut R. Association of below-knee atherosclerosis to medial arterial calcification in diabetes mellitus // Diabetes Res Clin Pract. -1995. -29(3). - P. 169-172.

4. Camafort M., Alvarez-Rodrigues H., Munoz-Torrerot J. F. et al. Glucose control and outcome in

patients with stable diabetes and previous coronary, cerebrovascular or peripheral artery disease. finding from the FRENA registry // Diabet Med. - 2011. -Vol. 28(1). - P. 73-78.

5. Kum S., TanY. K., Tang T.Y., SchmidtA., Scheinen D., Ferraresi R. et al. First in Man Experience with Percutaneous Deep Vein Arterialization for the Treatment of No-Option Critical Limb Ischemia // J Endovasc Ther. - 2017. - Vol. 24(5). - P. 619-626. -DOI: 10.1177/1526602817719283.

6. Kalish J., Eslami M., Gillespie D., Schermerhorn M., Rybin D., Doros G. et al. Routine use of ultrasound guidance in femoral arterial access for peripheral vascular intervention decreases groin hematoma rates // J Vasc Surg. - 2015. - Vol. 61. - P. 1231-1238.

7. Hackl G., Gary T., Belaj K., Hafner F., Eller P., Brodmann M. Risk factors for puncture site complications after endovascular procedures in patients with peripheral arterial disease // Vasc Endovascular Surg. - 2015. - Vol. 49. -P. 160-165.

8. Siracuse J. J. et al. Common femoral artery antegrade and retrograde approaches have similar access site complications // Journal of Vascular Surgery. - 2019. - Vol. 69(4). - P. 1160-1166.

9. Tonnesen K. H., Sager P., Karle A., Henriksen L., Jorgensen B. Percutaneous transluminal angioplasty of the superficial femoral artery by retrograde catheterization via the popliteal artery // Cardiovasc Interv Radiol. - 1988. - Vol. 11. - P. 127-131.

10. Htun W. W., Kyaw H., Aung Y. L. et al. Primary retrograde tibio pedal approach for endovascular intervention of femoropopliteal disease // Cardiovascular Revascularization Medicine. -2020. - Vol. 21(2). - P. 171-175.

11. SadekM., Ellozy S. H., Turnbull I. C., Lookstein R. A., Marin M. L., Faries P. L., Improved outcomes are associated with multilevel endovascular intervention involving the tibial vessels compared with isolated tibial intervention // J. Vasc. Surg. -2009. - Vol. 49(3). - P. 638-643.

12. Scheinert D., Laird J. R., Schröder M. et al. Excimer laser-assisted recanalization of long, chronic superficial femoral artery occlusions // J Endovasc Ther. - 2001. - Vol. 8. - P. 156-166.

13. Aihara H., Soga Y., Mii S. et al. Comparison of long-term outcome after endovascular therapy versus bypass surgery in claudication patients with Trans-Atlantic InterSociety Consensus-II C and D

femoropopliteal disease // Circ J. - 2014. - Vol. 78.

- P. 457-464.

14. Patel A., Parikh R., Htun W., Bellavics R., Coppola J.T., Maw M. et al. Transradial versus tibiopedal access approach for endovascular intervention of superficial femoral artery chronic total occlusion // Cardiovasc Interv. - 2018. - Vol. 92(7). - P. 1338-1344.

15. Ruzsa Z., Bellavics R., Nemes B., Huttl A., Nyerges A., Sotonyi P. et al. Combined transradial and transpedal approach for femoral artery interventions // JACC Cardiovasc Interv. - 2018.

- Vol. 11(11). - P. 1062-1071. - DOI: 10.1016/j. jcin.2018.03.038.

References

1. Norgren, L., Hiatt, W. R., Dormandy, J. A. et al. (2007). Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). J Vasc Surg, 45, 5-67.

2. Faglia, E., Paola, L. D., Clerici, G., Clerissi, J. Graziani et al. (2005). Peripheral angioplasty as the first-choice revascularization procedure in diabetic patients with critical limb ischemia: prospective study of 993 consecutive patients hospitalized and followed between 1999 and 2003. J Vacs Endovasc Surg, 29(6), 620-627.

3. Chantelau, E., Lee, K. M., Jungblut, R. (1995). Association of below-knee atherosclerosis to medial arterial calcification in diabetes mellitus. Diabetes Res Clin Pract, 29(3), 169-172.

4. Camafort, M., Alvarez-Rodrigues, H., Munoz-Torrerot, J. F. et al. (2011). Glucose control and outcome in patients with stable diabetes and previous coronary, cerebrovascular or peripheral artery disease. finding from the FRENA registry. Diabet Med, 28(1), 73-78.

5. Kum, S., Tan, Y. K., Tang, T. Y., Schmidt, A., Scheinert, D., Ferraresi, R. et al. (2017). First in Man Experience with Percutaneous Deep Vein Arterialization for the Treatment of No-Option Critical Limb Ischemia. J Endovasc Ther, 24(5), 619-626, DOI: 10.1177/1526602817719283.

6.Kalish, J.,Eslami,M., Gillespie,D., Schermerhorn, M., Rybin, D., Doros, G. et al. (2015). Routine use of ultrasound guidance in femoral arterial access for peripheral vascular intervention decreases groin hematoma rates. J Vasc Surg, 61, 1231-1238.

7. Hackl, G., Gary, T., Belaj, K., Hafner, F., Eller, P., Brodmann, M. (2015). Risk factors for puncture site complications after endovascular procedures in patients with peripheral arterial disease. Vasc Endovascular Surg, 49, 160-165.

8. Siracuse, J. J. et al. (2019). Common femoral artery antegrade and retrograde approaches have similar access site complications. Journal of Vascular Surgery, 69(4), 1160-1166.

9. Tonnesen, K. H., Sager, P., Karle, A., Henriksen, L., Jorgensen B. (1988). Percutaneous transluminal angioplasty of the superficial femoral artery by retrograde catheterization via the popliteal artery. Cardiovasc Interv Radiol, 11, 127-131.

10. Htun, W. W., Kyaw, H., Aung, Y. L. et al. (2020). Primary retrograde tibio pedal approach for endovascular intervention of femoropopliteal disease. Cardiovascular Revascularization Medicine, 21(2), 171-175.

11. Sadek, M., Ellozy, S. H., Turnbull, I. C., Lookstein, R. A., Marin, M. L., Faries, P. L. (2009). Improved outcomes are associated with multilevel endovascular intervention involving the tibial vessels compared with isolated tibial intervention. J. Vasc. Surg, 49(3), 638-643.

12. Scheinert, D., Laird, J. R., Schröder, M. et al. (2001). Excimer laser-assisted recanalization of long, chronic superficial femoral artery occlusions, J Endovasc Ther, 8, 156-166.

13. Aihara, H., Soga, Y., Mii, S. et al. (2014). Comparison of long-term outcome after endovascular therapy versus bypass surgery in claudication patients with Trans-Atlantic InterSociety Consensus-II C and D femoropopliteal disease. Circ J, 78, 457-464.

14. Patel, A., Parikh, R., Htun, W., Bellavics, R., Coppola, J. T., Maw M. et al. (2018). Transradial versus tibiopedal access approach for endovascular intervention of superficial femoral artery chronic total occlusion. Cardiovasc Interv, 92(7), 13381344.

15. Ruzsa, Z., Bellavics, R., Nemes, B., Hüttl, A., Nyerges, A., Sotonyi, P. et al. (2018). Combined transradial and transpedal approach for femoral artery interventions. JACC Cardiovasc Interv, 11(11), 1062-1071, DOI: 10.1016/j. jcin.2018.03.038.

АЯЦТЫЦ АУЫР ИШЕМИЯСЫ КЕЗ1НДЕ БАСТАПЦЫ РЕТРОГРАДТЫЦ ТИБИО-ПЕДАЛЬДЫ ХИРУРГИЯЛЫЦ ЖОЛЫН ЦОЛДАНУ

*Т.К. Таджибаев, А.А. Баубеков, Н.О. Омаров, А.Ц. Нусшацынов,

С.Т. НYрмаFанбет

«Private Clinic Almaty» ЖШС, Казахстан, Алматы

*Корреспондент автор

Ацдатпа

Tepi аркыды кан тамырдарыныц араласуынан кешнп ец жиi кездесетш аскынудар Kipy орнындагы аскынудар бодып табыдады. Ретроградтык дистальды код жeткiзyдi пайдалану дэстYpлi феморальды код жeткiзyмeн салыстырганда пункция орнында eдeyдi аскынудардыц каyпiн азайтады.

Мацсаты. Б^д зерттеудщ максаты теменп аяктыц сыни ишемиясы бар емдедушшерде феморо-попдитальды жэне инфрапопдитедьды сегменттершщ созыдмалы окклюзиядарын реваскудяризациядау Yшiн бастапкы ретроградтык дистальды тэсшдщ тиiмдiдiгi мен каушаздЫн аныктау бодды.

Материалдар мен эд1стер. Алматы Private Clinic Аяк сактау орталыгында 2022 жыддыц кацтарынан 2024 жыддыц тамызына дeйiн 18 наукаска peтpоспeктивтi талдау жасалды. Пациенттер кедес критерийдер бойынша тандалды: Рудерфорд классификациясы бойынша 3,4,5 санаттары жэне Фонтейн классификациясы бойынша 3,4 кeзeцдepi бар наукастар; инфрапопдитеальды сeгмeнтiнiн катысуымен немесе онсыз фeмоpопопдитальдi закымдану; аяктыц бip немесе бipнeшe бедтыр сегментшщ артерияда-рында кан агымыныц болуы; пациeнттepдiн акпараттандырыдган кeдiсiмi.

Нзтижелер1. Процедураныц сэттшп 100% бодды. Наукастардыц орташа жасы 74±5 жасты к¥рады. Пациенттердщ кепшiдiгi эйеддер бодды (66,7%). ^ант диабeтi (66,7%), артериядык гипертен-зия (55,5%), жYpeктiн ишемиядык ауруы (38,9%) жэне гиперлипидемия (77,8%) сиякты катар жYpeтiн аурудар аныкталды. Кеп жагдайда тацдау a.tibialis anterior 13 (72,2%) бодды. 14 жагдайда (77,8%) стент коюмен бipiктipiдгeн балдонды ангиопластика жасалды. Барлык араласудардыц iшiндe пункция орнында аздаган кан кету 1 жагдайда (5,5%) байкалды. Ешбip жагдайда eлeyлi кан кетудер, гематомалар, жYpeк-тамыр жYЙeсi тарапынан жагымсыз к¥быдыстар немесе елiм бeдгiдepi бодган жок. Барлык пациенттер ишемиядык себептермен катысты ауырсынулары жeнiддeндi.

Кррытынды. Ретроградты бipiншiдiк дистальды эдю техникалык т^ргыдан карапайым жэне аскынулары азырак бодады. Б^д эдют гематоманыц пайда боду каyпi жогары кYpдeдi eмдeдyшiдepдe нeгiзгi эдiс ретвде немесе антеградтык феморальды эдiскe балама peтiндe пайдалануга бодады.

Тушн свздер: бастащы ретроградтыц тибио-педальды хирургиялыц жолы, бастащы ретрогрдтыц дистальды хирургиялыц жолы, аяцтыц артерияларыныц критикалыц ишемиясы, АКИ.

ПРИМЕНЕНИЕ ПЕРВИЧНОГО РЕТРОГРАДНОГО ТИБИО-ПЕДАЛЬНОГО ДОСТУПА У ПАЦИЕНТОВ С КРИТИЧЕСКОЙ ИШЕМИЕЙ НИЖНИХ КОНЕЧНОСТЕЙ

*Т.К. Таджибаев, А.А. Баубеков, Н.О. Омаров, А.К. Нусипакынов,

С.Т. Нурмаганбет

ТОО «Private Clinic Almaty», Казахстан, Алматы *Корреспондирующий автор

Аннотация

Наиболее частыми осложнениями после чрескожных сосудистых вмешательств являются осложнения в месте доступа. Использование ретроградного дистального доступа позволяет снизить риски значимых осложнений в месте пункции по сравнению с традиционным бедренным доступом.

Целью данного исследования было определение эффективности и безопасности первичного ретроградного дистального доступа для реваскуляризации хронических окклюзий бедренно-подколенного и берцового сегментов у пациентов с критической ишемией нижних конечностей.

Материалы и Методы. Проведен ретроспективный анализ 18 пациентов в Центре спасения конечностей клиники Private Clinic Almaty с января 2022 года по август 2024 года. Пациенты отбирались по следующим критериям: пациенты с 3,4,5 категорями по классификации Рудерфорда и 3,4 стадиями по классификации Фонтейна; поражение бедренно-подколенного с вовлечением или без вовлечения берцового сегмента; наличие кровотока в одном или нескольких мегстральных артерий голени и стопы; информированное согласие пациентов на вмешательство.

Результаты. Успешность процедуры составил 100%. Средний возраст пациентов составил 74±5 лет. Большинство пациентов были женщинами (66,7%). Диагностированы такие сопутствующие заболевания, как сахарный диабет (66,7%), артериальная гипертензия (55,5%), ишемическая болезнь сердца (38,9%) и гиперлипидемия (77,8%). Артерией выбора в большинстве случаев была передняя большебер-цовая артерия 13 (72,2%). Из всех вмешательств малое кровотечение в месте пункции наблюдалось в 1 случае (5,5%). Ни в одном случае не было признаков значимого кровотечения, гематомы, нежелательных сердечно-сосудистых событий или смерти. У всех пациентов наблюдалось купирование болевого синдрома ишемического характера.

Выводы. Ретроградный первичный дистальный доступ технически проще и имеет тенденцию к меньшему количеству осложнений. Этот метод может быть применен в качестве основного доступа или как альтернатива антеградному бедренному доступу у сложных пациентов с высоким риском образования гематомы.

Ключевые слова: первичный ретроградный тибио-педальный доступ, первичный ретроградный дистальный доступ, критическая ишемия нижних конечностей, КИНК, заболевания периферических артерий, ЗПА.

АВТОРЛАР ТУРАЛЫ

Таджибаев Талгат Кадыралиевич - Алматы Приват клиникасыньщ кан тамырлары хирурп, докторант, e-mail: [email protected], ORCID: https://orcid.org/0000-0002-9007-063X. Баубеков Альжан Алкешевич - Алматы Приват клиникасыныц кан тамырлары хирургиясы бeлiмшщ мецгерушю, кан тамырлары хирурп, докторант, ORCID: https://orcid.org/0000-0001-7197-4871.

Омаров Нурлыбек Оразкелиевич -Алматы Приват клиникасыныц хирурп, ORCID: https://orcid. org/0000-0002-8885-817X.

Нуссипакунов Арман Кыдыркулович - Алматы Приват клиникасыныц кан тамырлары хирурп, ORCID: https://orcid.org/0009-0008-5644-8222.

Нурмаганбет Самал Тиморовна - Алматы Приват клиникасыныц кан тамырлары хирурп, ORCID: https://orcid.org/0000-0002-0989-4843.

ОБ АВТОРАХ

Таджибаев Талгат Кыдыралиевич - сосудистый хирург Приват Клиники Алматы, докторант, [email protected], ORCID: https://orcid.org/0000-0002-9007-063X.

Баубеков Альжан Алькешевич - руководитель отделения сосудистой хирургии Приват Клиники Алматы, сосудистый хирург, докторант, ORCID: https://orcid.org/0000-0001-7197-4871. Омаров Нурлыбек Оразкелиевич - хирург Приват Клиники Алматы, ORCID: https://orcid.org/0000-0002-8885-817X.

Нуссипакынов Арман Кыдыркулович - сосудистый хирург Приват Клиники Алматы, ORCID: https://orcid.org/0009-0008-5644-8222.

Нурмаганбет Самал Тиморовна - сосудистый хирург Приват Клиники Алматы, ORCID: https:// orcid.org/0000-0002-0989-4843.

ABOUTAUTHORS

Tajibayev Talgat Kadyralievich - vascular surgeon at the Private Clinic Almaty, doctoral candidate,

e-mail: [email protected], ORCID: https://orcid.org/0000-0002-9007-063X.

Baubekov Alzhan Alkeshevich - Head of the Department of Vascular Surgery at the Private Clinic Almaty,

vascular surgeon, doctoral candidate, ORCID: https://orcid.org/0000-0001-7197-4871.

Omarov Nurlybek Orazkelievich - surgeon at the Private Clinic Almaty, ORCID: https://orcid.org/0000-

0002-8885-817X.

Nussipakynov Arman Kydyrkulovich - vascular surgeon at the Private Clinic Almaty, ORCID: https:// orcid.org/0009-0008-5644-8222.

Nurmaganbet Samal Timorovna - vascular surgeon at the Private Clinic Almaty, ORCID: https://orcid. org/0000-0002-0989-4843.

Conflict of interest. All authors declare that there is no potential conflict of interest requiring disclosure in this article.

Contribution of the authors. All the authors of this article have made an equal contribution to its writing. Financing. Absent

Article submitted: 31.07.2024 Accepted for publication: 9.08.2024

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