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Том 153, кн. 1
УЧЕНЫЕ ЗАПИСКИ КАЗАНСКОГО УНИВЕРСИТЕТА
Физико-математические пауки
2011
Ильясов К.А. Количественное измерение диффузии in vivo методом магпитпо-резопапспой томографии // Учен. зап. Казан, уп-та. Сер. Физ.-матем. пауки. 2011. Т. 153, кп. 1. С. 17 37.
УДК 539.143.43
КОЛИЧЕСТВЕННОЕ ИЗМЕРЕНИЕ ДИФФУЗИИ IN VIVO МЕТОДОМ МАГНИТНО-РЕЗОНАНСНОЙ ТОМОГРАФИИ
К.А. Ильясов
Аннотация
Рассмотрены физические аспекты получения и количественной обработки диффузи-ошго-взвешеппых магпитпо-резопапспых изображений. Обсуждены источники возникновения погрешностей и искажений диффузиоппо-взвешеппых изображений и методы их коррекции и компенсации. Измеряемые количественные характеристики диффузии различаются в зависимости от микроструктуры тканей in vivo, и при корректном измерении и анализе опи могут служить индикатором патологий, в частности связанных с изменениями структуры белого вещества головного мозга.
Ключевые слова: ядерный магнитный резонанс, магпитпо-резопапспая томография. диффузиошю-взвешеппая МРТ, диффузиошю-тепзорпая МРТ, тензор диффузии, искажения токами Фуко, коррекция искажений, количественные измерения, калибровка измерений.
Summary
К,A, Ilyasuv. Quantitative Diffusion Magnetic Resonance Imaging In Vivo.
The paper deals with physical and mathematical basics for diffusion weighted MR imaging and analysis. Different sources of image distortions and corresponding methods of their correction are discussed. When accurately measured, quantitative diffusion parameters can indicate pathologies in tissue microstruct.ure and serve as a clinical diagnostic tool for different diseases such as, for example, white matter degeneration.
Key words: nuclear magnetic resonance, MRI, diffusion weighted MRI, diffusion tensor MRI, diffusion tensor, eddy currents distortions, correction of distortions, quantitative analysis, measurement calibration.
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Поступила в редакцию 06.07.10
Ильясов Камиль Ахатович кандидат физико-математических паук, доцепт кафедры общей физики и ученый секретарь учебпо-паучпого центра «Медицинская физика» Казанского (Приволжского) федерального университета. Е-шаП: ktimil.ilyasovegmail.com
