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environments, impacting performance.
Integration with existing systems. Seamless integration of graphene biosensors into clinical and industrial workflows requires standardized protocols and compatibility with existing technologies.
Regulatory hurdles. Approval for graphene-based devices in healthcare and environmental sectors requires extensive validation and safety testing. Conclusion
Graphene biosensors represent a transformative innovation in the field of biosensing, offering unprecedented sensitivity, specificity, and versatility. Despite challenges in fabrication and integration, ongoing advancements in nanotechnology and materials science are expected to drive the widespread adoption of graphene biosensors in medicine, environmental monitoring, and beyond. With continued research and collaboration, graphene-based biosensors hold the potential to revolutionize diagnostics and improve quality of life on a global scale. References:
1. Novoselov, K. S., et al. (2004). Electric field effect in atomically thin carbon films. Science, 306(5696), 666-669.
2. Pumera, M., et al. (2019). Graphene in biosensing. Trends in Biotechnology, 37(7), 825-836.
3. Geim, A. K., & Novoselov, K. S. (2007). The rise of graphene. Nature Materials, 6(3), 183-191.
© Geldiyeva A., 2024
УДК 57
Gylychdurdyyew G.,
student.
Oguz han Engineering and Technology university of Turkmenistan.
Ashgabat, Turkmenistan.
EXPLORING THE ROLE OF ARTEMISIA ANNUA IN ENHANCING GUT HEALTH AND PERFORMANCE IN BROILER DIETS
Annotation
The poultry industry is increasingly focused on sustainable and natural solutions to enhance productivity while maintaining health standards, especially in the context of antibiotic restrictions. Artemisia annua (sweet wormwood) has emerged as a potential alternative feed additive due to its antimicrobial, antioxidant, and immunomodulatory properties. This study examines the role of A. annua in improving gut health and performance in broiler chickens.
Key words:
industry, sustainable, natural solutions, productivity, performance.
The poultry industry is increasingly focused on sustainable and natural solutions to enhance productivity while maintaining health standards, especially in the context of antibiotic restrictions. Artemisia annua (sweet wormwood) has emerged as a potential alternative feed additive due to its antimicrobial, antioxidant, and immunomodulatory properties. This study examines the role of A. annua in improving gut health and performance in broiler chickens. Key findings highlight its positive impact on gut microbial balance, intestinal morphology, and overall growth performance, offering a natural and efficient alternative for broiler diets.
Gut health is pivotal for the optimal performance of broilers, directly affecting nutrient absorption,
immunity, and overall growth. Antibiotics have historically played a significant role in enhancing gut health, but their overuse has led to resistance and regulatory bans. As a result, natural feed additives like Artemisia annua are gaining attention for their potential to support gut health and improve broiler productivity without harmful side effects.
Artemisia annua, a medicinal herb known for its active compound artemisinin, has demonstrated broad-spectrum antimicrobial, antioxidant, and anti-inflammatory activities. Its potential as a functional feed ingredient in broiler diets lies in its ability to influence gut microbial populations and support digestive and immune functions.
Phytochemical Properties of Artemisia annua
The bioactive compounds in A. annua contribute to its efficacy in enhancing broiler health and performance. These include:
Artemisinin: Known for its antimalarial and antimicrobial properties, it helps regulate gut microbiota.
Flavonoids: These antioxidants reduce oxidative stress and inflammation in intestinal tissues.
Essential Oils: Possessing antibacterial and antifungal effects, they create a favorable gut environment.
Saponins and Tannins: These compounds exhibit antimicrobial activity and support gut lining integrity.
Impact on Gut Health
Microbial Modulation:
A. annua promotes beneficial gut bacteria such as Lactobacillus and suppresses pathogenic strains like Escherichia coli and Clostridium perfringens.
Its antimicrobial compounds create a balanced gut environment conducive to nutrient absorption.
Enhanced Intestinal Morphology:
Dietary inclusion of A. annua improves intestinal villus height and crypt depth, increasing the surface area for nutrient uptake.
Reduction in Inflammation:
The anti-inflammatory effects of flavonoids and artemisinin protect intestinal tissues from stress-induced damage, maintaining gut integrity.
Effects on Broiler Performance
Growth Performance:
Studies show that broilers supplemented with A. annua exhibit higher weight gain and improved feed conversion ratios (FCR).
Immune Function:
A. annua enhances immune response by modulating inflammatory pathways and reducing gut-associated infections.
Stress Mitigation:
Its antioxidant properties help broilers cope with environmental and dietary stressors, ensuring consistent growth and productivity.
Challenges and Research Directions
While A. annua shows significant potential, challenges remain in its practical application:
Standardization: Variability in bioactive compound content necessitates consistent quality control during production.
Toxicity Studies: Long-term safety assessments are required to ensure no adverse effects on poultry or consumers.
Optimal Dosage: Research is needed to determine the most effective dosage levels for different broiler breeds and production systems.
Economic Feasibility: Widespread adoption will depend on cost-effective cultivation and processing methods.
Artemisia annua represents a promising natural feed additive for enhancing gut health and broiler performance. Its antimicrobial, antioxidant, and anti-inflammatory properties contribute to better gut integrity, nutrient absorption, and immune function. Future research and standardization efforts will be essential to unlock its full potential as a sustainable alternative in poultry nutrition.
Список использованной литературы:
1. Ferreira, J. F., & Luthria, D. L. (2010). Artemisia annua: Phytochemical and Pharmacological Aspects. Springer.
2. Wang, J., et al. (2018). "Effects of Herbal Feed Additives on Gut Health and Performance in Poultry." Poultry Science Journal, 97(4), 3456-3464.
3. Kim, D. H., & Lillehoj, H. S. (2019). "Role of Medicinal Plants in Modulating Gut Microbiota in Poultry." Frontiers in Veterinary Science.
© Gylychdurdyyew G., 2024
УДК 57
Hydyrova A.,
student.
Oguz han Engineering and Technology university of Turkmenistan.
Ashgabat, Turkmenistan.
PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF ZYGOPHYLLUM FABAGO
Annotation
Zygophyllum fabago, commonly known as Syrian bean-caper or bean-caper, is a member of the Zygophyllaceae family. It is a perennial shrub found in arid and semi-arid regions. Known for its resilience in harsh conditions, Z. fabago has been traditionally used in folk medicine for treating a variety of ailments, including inflammation and digestive disorders. Recent studies focus on its phytochemical constituents and antimicrobial properties, revealing its potential as a source of bioactive compounds.
Key words:
Zygophyllum fabago, traditionally, medicine, inflammation, phytochemical constituents.
Zygophyllum fabago, commonly known as Syrian bean-caper or bean-caper, is a member of the Zygophyllaceae family. It is a perennial shrub found in arid and semi-arid regions. Known for its resilience in harsh conditions, Z. fabago has been traditionally used in folk medicine for treating a variety of ailments, including inflammation and digestive disorders. Recent studies focus on its phytochemical constituents and antimicrobial properties, revealing its potential as a source of bioactive compounds.
Phytochemical Composition
Phytochemicals are natural compounds produced by plants, contributing to their defense mechanisms and offering therapeutic benefits for humans. In the case of Zygophyllum fabago, several key phytochemicals have been identified:
Alkaloids: These compounds exhibit anti-inflammatory, antimicrobial, and analgesic properties.
Flavonoids: Known for their antioxidant and anti-inflammatory activities, flavonoids protect cells from oxidative stress.
Saponins: These are known to possess antimicrobial, anti-inflammatory, and hemolytic activities.
